Moravia is the most important wine producing region in the republic. It is ocated along the Austrian and Slovakian Borders.

The climate is mild/continental with relatively low rainfall, on average a half to two-thirds that of Burgundy and Alsace which are on the same latitude.

Warm days and cold nights mean that ripening is slowed down. Clay and sand dominate the soil. Two thirds of production is given to white varieties which yield highly aromatic, fresh and fruity wines with good acidity. The total area under vine is 17,500 ha.

The most important wine region in the Czech Republic stretches from Znojmo to Uherské Hradiště. It consists of four Wine Sub-regions: Znojemská, Mikulovská, Velkopavlovická and Slovácká. It covers 17,529 hectares of vineyards, which represents 96 % of registered vineyards in the Czech Republic. The Morava (Moravia) Wine Region is the area, according to legends and archaeological sources, with the oldest viticultural and vinicultural tradition in the country. It lies around the 49th parallel, as well as the wine region of Champagne or the best wine regions of Germany. It consists of 308 wine municipalities and 1,142 vineyard sites, which are managed by over 17,618 vine-growers. The most municipalities and vine-growers can be found in the Slovácká Wine Sub-region, the largest area of vineyards is in the Mikulovská Wine Sub-region, close behind it is the Velkopavlovická. The largest wine municipalities are Velké Bílovice, Valtice, Mikulov and Čejkovice. According to a six-year measurement at the Wine Breeding Station in Velké Pavlovice, the average annual temperature reaches 12.4 °C, the average annual precipitation is 463 mm and the approximate annual sunshine duration is 1,700 hours. Although the growing season is shorter than in Western Europe, in most years, it is characterized by a higher heat intensity of the summer months, which allows the cultivation of varieties with late ripening grapes. The ripening process is slower, so more aromatic substances are concentrated in the grapes. Varietal representation almost copies the overall statistics of the Czech Republic – dominated by Grüner Veltliner and Müller Thurgau – the other ranks are divided by Riesling, Welschriesling, and from the red varieties, Blaufränkisch and St. Laurent.